Enhancing Social Interaction in Depression (SIDE study): protocol of a randomised controlled trial on the effects of a Cognitively Based Compassion Training (CBCT) for couples

Aguilar-Raab, Corina ; Jarczok, Marc N. ; Warth, Marco ; Stoffel, Martin ; Winter, Friederike ; Tieck, Maria ; Berg, Judith ; Negi, Lobsang Tenzin ; Harrison, Timothy ; Pace, Thaddeus W. W. ; Ditzen, Beate

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DOI:	https://doi.org/10.1136/bmjopen-2017-020448
URL:	https://bmjopen.bmj.com/content/8/9/e020448
Weitere URL:	https://pubmed.ncbi.nlm.nih.gov/30287601/
URN:	urn:nbn:de:bsz:180-madoc-676259
Dokumenttyp:	Zeitschriftenartikel
Erscheinungsjahr:	2018
Titel einer Zeitschrift oder einer Reihe:	BMJ open
Band/Volume:	8
Heft/Issue:	Article e020448
Seitenbereich:	1-15
Ort der Veröffentlichung:	London
Verlag:	BMJ Publishing Group
ISSN:	2044-6055
Sprache der Veröffentlichung:	Englisch
Einrichtung:	Fakultät für Sozialwissenschaften > Klinische Psychologie, Interaktions- und Psychotherapieforschung (Aguilar-Raab 2023-)
Bereits vorhandene Lizenz:	Creative Commons Namensnennung, nicht kommerziell 4.0 International (CC BY-NC 4.0)
Fachgebiet:	150 Psychologie
Abstract:	Introduction Positive social interactions (PSIs) and stable relationships can exert substantial benefits on health. However, patients suffering from depression benefit less from these health-promoting effects. Moreover, relationship quality and even partners’ health has been found to be negatively affected by depressive symptomatology, which may result in overall impairments in social functioning of a romantic couple. Psychobiological research indicates that these impairments may be accompanied by a maladaptive regulation of the patient’s neuroendocrine response to external stressors. Concerning the improvement of social functioning, first studies showed promising results of “Cognitively Based Compassion Training (CBCT®)”. However, randomised trials are still scarce. Previous programmes did not involve participation of the patient’s romantic partner. Therefore, the present study aims to investigate whether a CBCT® programme adapted for couples (CBCT®-fC) can improve depressive symptoms, distress, social interaction skills and the neurobiological regulation of stress. Methods and analysis Couples with the female partner suffering from depression will be invited to participate in a pre-to-post intervention assessment on two consecutive days, respectively, involving a standardised PSI task, eye-tracking, ECG recordings, saliva-sampling, blood-sampling and questionnaire data. After baseline assessment, participating couples will be randomised to either a 10 week CBCT®-fC or to a treatment as usual control condition. The primary endpoint is the reduction of depressive symptoms measured by the Hamilton Depression Rating Scale. Secondary outcomes encompass self-rated depression (Beck Depression Inventory), attention towards the partners face during PSI (eye tracking), stress-related biomarkers (cortisol, α-amylase, interleukin (IL)-1ß/IL-6, heart rate variability), methylation of oxytocin-receptor-genes and serotonin-transporter-genes and self-ratings of psychological constructs such as relationship quality and empathy.
Zusätzliche Informationen:	Verfasser hier: Harrison, Tim

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